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![glp 1 amino acid sequence 2 [Tyr34] (1-34), human Peptide sequences and molecular structures](https://www.researchgate.net/publication/326447155/figure/fig1/AS:659537950416896@1534257509489/Peptide-sequences-and-molecular-structures-of-FDA-approved-GLP-1-RAs.png)
Several case reports have documented individual patients with lipedema who experienced symptomatic improvement and some reduction in limb circumference while taking incretin-based medications, particularly semaglutide
![glp 1 amino acid sequence 2 [Tyr34] (1-34), human Peptide sequences and molecular structures](https://www.researchgate.net/publication/42539429/figure/fig4/AS:651179054866434@1532264593702/Amino-Acid-Structure-of-Native-Human-GLP-1-and-Liraglutide.png)
A healthcare provider may prescribe the injection for patient-specific needs, but compounded products should only be used under medical supervision
![glp 1 amino acid sequence 2 [Tyr34] (1-34), human Peptide sequences and molecular structures](https://www.researchgate.net/profile/Sung-Gun-Kim-2/publication/50594650/figure/fig1/AS:543097140375552@1506495856985/DNA-and-corresponding-protein-sequences-of-GLP-1-A-and-schematic-structure-of.png)
*Correspondence: Alessandro Pocai, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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